Antabuse (Disulfiram) - 200mg (100 Tablets)
| Main Use |
Active Integredient |
Marketed Name |
| Alcoholism - deterrent to alcohol |
Disulfiram |
Antabuse® |
Disulfiram is used to treat alcohol dependence. It is most helpful if you are motivated to stop drinking and are willing to take the medicine under supervision. Medicines are not generally used alone to treat alcohol abuse or dependence. The best treatment is a combination of medicine and counseling.
ACTION: Disulfiram inhibits aldehyde dehydrogenase, the oxidative enzyme of acetaldehyde, a metabolite of alcohol. The latter is accumulated in the blood, thus producing unpleasant sysmptoms of disulfiram-alcohol reaction when a patient has taken small amounts of alcohol.
INDICATIONS: Adjunctive treatment of chronic alcoholism
SAFETY PROFILE: Diabetes, epilepsy, hepatic/renal impairment, hypothyroidism, cerebral damage, elderly. Liver function and blood tests should be monitored regularly. Pregnancy and lactation.
ADVERSE EFFECTS: Drowsiness, fatigue, lassitude, psychotic reactions, peripheral and optic neuropathies, hepatotoxicity, garlic-like or metallic after-taste, GI upset, body odour, bad breath, headache, impotence.
DOSAGE: Adult 800mg as a single dose on the 1st day treatment, reduced by 200mg daily.
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