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United Pharmacies (UK)
::
General
:: Cordarone - 200mg (30 Tablets)
Cordarone - 200mg (30 Tablets)
CORDARONE X 200mg 30s
Brand Name:
CORDARONE X
Drug name:
Amiodarone
Manufacturer:
sanofi-aventis
Other names:
Form:
Tablets
Dosage:
200mg
Packaging:
Box containing 30 tablet (3 X strip of 10 tablets)
Class:
Amiodarone is a Class III antiarrhythmic agent prolonging the action potential duration and hence refractory period of atrial, nodal and ventricular tissues, thereby giving a very broad spectrum of activity. An increase in the refractory period of the atrial cells is a major contributing action to the control of atrial tachyarrhythmias.
Country of Origin:
Australia
Site and Mode of Action
A reduction in the permeability of the A-V node, both anterograde and retrograde, explains the efficacy of the medicine in nodal tachycardias caused by re-entry through the A-V node.
Its action on ventricular arrhythmias is explained by a number of mechanisms. The effect on the atrium and A-V node results in a reduction in the frequency of stimuli reaching the ventricle thus giving the ventricular cell mass time to repolarise in cases where there has been desynchronisation of the refractory periods. Furthermore, a lengthening of the refractory period of the His-Purkinje system and ventricular contractile fibres reduces or prevents micro re-entry. Amiodarone increases coronary blood flow, decreases cardiac oxygen requirements without producing negative inotropic effects and also suppresses ectopic pacemakers, and this is particularly valuable in arrhythmias associated with ischaemic damage or angina pectoris.
The site and mode of action of amiodarone can be summarised in terms of its effect on myocardial electrophysiology.
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Quantity:
7+ Items
Price:
£21.00
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Hair Pharmacy
All prices are quoted in British Pounds.